Are Doctors Weight Loss Prescriptions Really Safe?

Most Common Prescription Weight Loss Medications in Singapore

1. Orlistat (Xenical, Alli)

Orlistat stands as one of the most prevalent weight loss prescriptions in Singapore. This medication operates by inhibiting lipase, an enzyme crucial for fat breakdown within the diet. By blocking the absorption of approximately 30% of dietary fat, the unabsorbed fat is excreted undigested, which supports weight loss.

Potential Side Effects:

Orlistat's side effects are primarily gastrointestinal due to its method of blocking fat absorption. These can include:

- Diarrhea

- Flatulence with discharge

- Oily or fatty stools

- Frequent bowel movements

- Rarely, liver injury

Scientifically, Orlistat has proven its effectiveness in facilitating weight loss. A landmark study published in the "Annals of Pharmacotherapy" in 2006 showed that individuals using Orlistat lost significantly more weight compared to those taking a placebo, with an average weight reduction of about 5% within three months. It should be noted that Orlistat can also hinder the absorption of fat-soluble vitamins, necessitating possible supplementation [[❞]](https://novi-health.com/library/prescription-weight-loss-pills-in-singaporewhich-ones-actually-work).

2. Phentermine (Panbesy, Duromine, Qsymia)

Phentermine is another widely used prescription in Singapore for weight loss. It acts as an appetite suppressant by influencing the central nervous system to increase levels of neurotransmitters such as norepinephrine, serotonin, and dopamine, which aid in reducing appetite.

Potential Side Effects:

The use of Phentermine is not without risks, particularly concerning the cardiovascular system:

- Increased heart rate

- Elevated blood pressure

- Nervousness

- Insomnia

- Dry mouth

- Potential addictive properties, akin to amphetamines

Furthermore, Phentermine is linked with risks during pregnancy, including fetal abnormalities, which underscores its prescription for short-term use, typically less than 12 weeks. However, extended use may be considered under strict medical supervision.

Research underscores Phentermine's efficacy in weight management, with studies showing about a 3% weight loss after three months and between 5-7% after six months. More notable, a 2013 study in the journal "Obesity" found that a combination of Phentermine and Topiramate was even more effective, resulting in significant weight loss over 28 weeks [[❞]](https://novi-health.com/library/prescription-weight-loss-pills-in-singaporewhich-ones-actually-work).

Conclusion:

Both Orlistat and Phentermine are among the most common prescription weight loss medications in Singapore. They provide significant benefits for managing obesity but come with potential side effects that should not be overlooked. Users should engage in thorough discussions with their healthcare providers, considering all risks and benefits, before commencing treatment. This cautious approach ensures safety and promotes the best possible outcomes in weight loss journeys.